B. Elman
1985
Citations
0
Influential Citations
3
Citations
Journal
Tetrahedron
Abstract
Abstract Reaction of 2-chloro-6-cyanopyridine with aliphatic mono- and di-alcohols or ethylene glycols affords, depending on the reaction conditions, alkoxypyridines or imino ester pyridines or a mixture of both types of compounds. It is suggested that the product distribution is determined by the stability of an imidate anion formed as an intermediate. An improved synthesis of 2-chloro-6-cyanopyridine is also described.