Ying Zhou, Ying-juan Fang, Zhan-Feng Gong
Jul 1, 2009
Citations
1
Influential Citations
9
Citations
Journal
Chinese Journal of Natural Medicines
Abstract
Abstract Aim To study the chemical constituents of the roots of Valeriana officinalis L. Methods Chemical constituents were isolated by various column chromatographic techniques and their structures were elucidated by spectroscopic methods. Results A new sesquiterpene, orivalerianol (4β, 10α, 15-trihydroxy-aromadrendane) ( 1 ), and a new iridoid, monovalerianester A (aglycone of kanokoside A) ( 2 ) together with eight known compounds rulepidol ( 3 ), behenic acid ( 4 ), pinoresinol ( 5 ), valerenic acid ( 6 ), β-sitosterol ( 7 ), kanokoside A ( 8 ), prinsepiol-4- O -β- D -glucoside ( 9 ) and 8-hydroxypinoresinol-4 - O -β- D -glucoside ( 10 ) were obtained from the EtOAc extract ( 1∼6 ) and n -BuOH extract ( 7∼10 ). Conclusion Compounds 1 and 2 are new natural products.