Shuai Dong, D. Clive, Jin-Ming Gao
Dec 9, 2015
Citations
0
Influential Citations
2
Citations
Journal
Tetrahedron Letters
Abstract
[(tert-Butyldimethylsilyl)oxy]methanethiol [HSCH2OSiMe2Bu-t] is a nucleophilic reagent for introduction of a protected bivalent sulfur; this reagent is complementary to the electrophilic reagent p-MeC6H4SO2SCH2OSiMe2Bu-t. The thiol is prepared by the action of HSLi on tert-butyl(chloromethoxy)dimethylsilane [ClCH2OSiMe2Bu-t] and it reacts with alkyl bromides to give protected thiols.