T. Kamiyama, Y. Itezono, T. Umino
Jul 1, 1993
Citations
0
Influential Citations
23
Citations
Journal
The Journal of antibiotics
Abstract
The structure of tetrafibricin, a novel and potent fibrinogen receptor antagonist isolated from the culture broth of Streptomyces neyagawaensis NR0577, was determined. Tetrafibricin has a unique structure containing primary amine, conjugated tetraenoic acid, and polyhydroxy functionalities that is biosynthetically related to the polyene macrolide antibiotics.