Natasha L. Hungerford, Timothy D. W. Claridge, Mark P. Watterson
2000
Citations
0
Influential Citations
40
Citations
Journal
Journal of The Chemical Society-perkin Transactions 1
Abstract
The synthesis of a D-allo-5-(azidomethyl)tetrahydrofuran-2-carboxylate as an amino acid precursor (in which the carboxylic acid is cis to the azidomethyl substituent and trans to the diol moiety) is reported from D-ribose. The oligomerisation of this monomer to dimeric, tetrameric and octameric carbopeptoids is described. NMR studies into the solution structures of cyclohexylidene-protected oligomers and of a deprotected tetramer with eight free hydroxy groups are described.