Di-Fei Shen, Q. Tang, Ling Yan
Feb 1, 2010
Citations
0
Influential Citations
42
Citations
Quality indicators
Journal
British Journal of Pharmacology
Abstract
Background and purpose: Tetrandrine, a well‐known naturally occurring calcium antagonist with anti‐inflammatory, antioxidant and anti‐fibrogenetic activities, has long been used clinically for treatment of cardiovascular diseases such as hypertension and arrhythmia. However, little is known about the effect of tetrandrine on cardiac hypertrophy. The aims of the present study were to determine whether tetrandrine could attenuate cardiac hypertrophy and to clarify the underlying molecular mechanisms.