Xi Zhao, Gui Han, Hongkun Zhao
Nov 12, 2019
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0
Influential Citations
20
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Journal
Journal of Chemical & Engineering Data
Abstract
The equilibrium solubility of phenformin in 14 solvents of N,N-dimethylformamide (DMF), N-methyl-2-pyrrolidinone (NMP), dimethyl sulfoxide (DMSO), methanol, isopropanol, ethanol, n-propanol, 1,4-dioxane, n-butanol, isobutanol, acetonitrile, ethyl acetate, ethylene glycol (EG), and water was gained using the saturation shake-flask method over a temperature range of 278.15 to 323.15 K under pressure p = 101.2 kPa. The mole fraction solubility of phenformin in the above neat solvents increased as the temperature increased and had a variation trend in the different solvents: DMF > DMSO > NMP > EG > methanol > ethanol > ethyl acetate > n-propanol > isopropanol > n-butanol > isobutanol > water > acetonitrile > 1,4-dioxane. It was correlated using the nonrandom two-liquid model, modified Apelblat equation, λh equation, and the Wilson model. The obtained values of maximum root-mean-square deviation and relative average deviation gained via the four models were, respectively, 29.14 × 10–4 and 4.46 × 10–2. Also, th...