Marcin H. Kudzin, Z. Kudzin, J. Drabowicz
Apr 17, 2011
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0
Influential Citations
14
Citations
Journal
ChemInform
Abstract
1-Aminoalkylphosphonic acids (AA) as structural analogues of protein amino acids (AA), are important inhibitors of amino acids metabolism. One of the three methods which have contributed to the development of the chemistry of 1-aminoalkylphosphonic acids is the Ptcaminoalkylphosphonate (Phenylthiocarbamoylaminoalkylphosphonate) method which allows a time saving synthesis of structurally diverse AA of analytical purity on mmol-mol scale This review presents a comprehensive survey of this methodology development, with an emphasis on its scope and limitations.