P. Stevenson, M. Nieuwenhuyzen, Daire Osborne
Feb 27, 2002
Citations
0
Influential Citations
26
Citations
Journal
Chemical communications
Abstract
N-Acetyl-2-azetine undergoes Lewis acid catalysed [4 + 2]-cycloaddition with imines derived from aromatic amines and gave a 1:1 mixture of exo-endo diastereoisomeric azetidine cycloadducts which reacted further with aromatic amine, to give 2,3,4-trisubsitituted tetrahydroquinolines in good to excellent yield, predominantly as one diastereoisomer.