Y. Shiono, T. Murayama, Koetsu Takahashi
Jan 1, 2005
Citations
1
Influential Citations
56
Citations
Quality indicators
Journal
Bioscience, Biotechnology, and Biochemistry
Abstract
Three cyclohexenone derivatives, (4S,5S,6S)-5,6-epoxy-4-hydroxy-3-methoxy-5-methyl-cyclohex-2-en-1-one (1), (4R,5R)-4,5-dihydroxy-3-methoxy-5-methyl-cyclohex-2-en-1-one (2), and (4R,5S,6R)-4,5,6-trihydroxy-3-methoxy-5-methyl-cyclohex-2-en-1-one (3), were isolated from unpolished rice fermented with an xylariaceous endophytic fungus (strain YUA-026). The structures of three compounds were established on the basis of spectroscopic analyses and chemical conversion. The minimum inhibitory concentrations of 1 and 3 were 100 μg/ml and 400 μg/ml against Staphylococcus aureus, 100 μg/ml and 200 μg/ml against Pseudomonas aeruginosa, and 200 μg/ml and >400 μg/ml against Candida albicans, respectively. In addition, 1 and 3 exhibited phytotoxic activity against lettuce.