Sahaj Gupta, B. Kumar, B. Kundu
Nov 22, 2011
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0
Influential Citations
42
Citations
Journal
The Journal of organic chemistry
Abstract
An efficient synthesis toward highly diversified α-carboline derivatives via a three-component tandem reaction using acid chlorides, terminal alkynes, and 2-aminoindole hydrochlorides has been described. The salient feature of the one-pot strategy involves regioselective [3 + 3]-cyclocondensation and the presence of water in the reaction medium to facilitate cyclization. Nonaqueous conditions furnished products in poor yields.