T. Mukaiyama
Dec 1, 1977
Citations
1
Influential Citations
228
Citations
Quality indicators
Journal
Angewandte Chemie
Abstract
Titanium tetrachloride can accelerate numerous organic reactions. Valuable syntheses of, e.g., allyl sulfides, amides, enamines, and ketones are based upon transformations of functional groups with TiCl4. Particular mention should also be made of carbon-carbon linkage with TiCl4 which permits the synthesis of hydroxy ketones and carbonyl compounds of the Michael adduct type. TiCl4 reduced in situ is suitable for the reduction of chloroarenes or the linkage of two aldehyde molecules to give an alkene.