S. Boduroglu, Jouliana M. El Khoury, D. Venkat Reddy
Sep 1, 2005
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0
Influential Citations
31
Citations
Journal
Bioorganic & medicinal chemistry letters
Abstract
3-Pyridinylboronic acid is identified as a key sensing element for reversible sugar complexation in an aqueous solution at the physiological pH. The utility of a sensing element has been demonstrated through a simple colorimetric titration of glucose using absorption spectroscopy in the visible region. The mechanism of the high diol/triol binding affinity of pyridine boronic acid in the neutral pH is discussed based on the 1H and 11B NMR spectroscopic studies.