G. Sabitha, K. Reddy, G. K. Reddy
Sep 1, 2005
Citations
0
Influential Citations
39
Citations
Journal
Synlett
Abstract
The reaction of aldehydes with homoallyl alcohols in the presence of TMSI generated in situ from TMSCl and NaI produced 4-iodo-tetrahydropyrans in good yields as a mixture of diastereo- isomers, which are separated and characterized. These iodo pyrans are reported for the first time. This methodology was extended to the synthesis of (±)-centrolobine.