Jie Liu, Zhanchao Li, Pei Tong
Jan 12, 2015
Citations
0
Influential Citations
37
Citations
Journal
The Journal of organic chemistry
Abstract
A concise and facile synthetic protocol for the construction of the 2-γ-lactone chromanone skeleton has been achieved through a TMSI-promoted diastereoselective vinylogous Michael addition of siloxyfuran to 2-substituted chromones. The applicability of this method is demonstrated through the rapid access to the total syntheses of (±)-microdiplodiasone, (±)-lachnone C, and (±)-gonytolides C and G.