A. R. Singh, W. H. Lawrence, J. Autian
Oct 1, 1973
Citations
0
Influential Citations
30
Citations
Quality indicators
Journal
Journal of pharmaceutical sciences
Abstract
Abstract Seven adipates (dimethyl, diethyl, dipropyl, diisobutyl, di-n-butyl, di-2-ethylhexyl, and dicyclohexyl) were evaluated for their embryonic-fetal toxicity and teratogenic effects in rats, and the results were compared to those of a previous study with phtha- late esters. The data suggest that the adipates are less teratogenic than the comparable phthalates when administered during gestation in equivalent fractions of the respective I.D 50 doses.