K. Willett, Andrea E. Ulrich, R. Hites
Jun 27, 1998
Citations
49
Influential Citations
851
Citations
Quality indicators
Journal
Environmental Science & Technology
Abstract
The differential environmental fates and toxicities of the various hexachlorocyclohexane (HCH) isomers including lindane and isomers in the technical mixture will be the focus of this review. HCHs are one of the most widely used and most readily detected organochlorine pesticides in environmental samples. The relatively high volatility of HCH has led to global transport, even into formerly pristine locations such as the Arctic. Certain HCHs cause central nervous system, reproductive, and endocrine damage. Because γ-HCH is rapidly metabolized, the β-HCH isomer is consistently found in higher concentrations in human fat, blood, and breast milk. In contrast, α- and γ-HCH are the most prevalent isomers in soil, water, and air samples. The ratio of the α- to γ-isomers can be used to track global transport of HCHs. A new area of HCH research focuses on the selective degradation of the two α-HCH enantiomers in various environmental matrices. These HCH issues and recommendations for future HCH research are presen...