N. Phatak, G. A. Emerson
Oct 1, 1936
Citations
0
Influential Citations
4
Citations
Journal
Journal of Pharmacology and Experimental Therapeutics
Abstract
Toxicity of the alkyl esters of 2-furoic acid on intraperitoneal injection in rats increases from methyl to propyl. Relative insolubility of the butyl and amyl esters may account for the fact that they are less toxic than the lower esters. The alkyl benzoates from methyl to amyl exhibit no significant local anesthetic action, while, in the corresponding furoates local anesthetic activity increases throughout the series from methyl to amyl.