A. Kadous, F. Matsumura
Sep 1, 1982
Citations
0
Influential Citations
8
Citations
Journal
Archives of Environmental Contamination and Toxicology
Abstract
Major metabolic products of dieldrin, endrin, and photodieldrin were identified in the American cockroach, and their toxicities were tested in the male German cockroach. Among dieldrin metabolites tested, F-1 the major fecal metabolite in rats, was most toxic to the German cockroach. The most toxic metabolite of endrin was 3-hydroxyendrin. The toxic endrin metabolite to the rat, 12-ketoendrin, was not so toxic to the German cockroach. The most consistent major metabolic product of photodieldrin, U-1, which is identical to the major urinary metabolite in the rat, was less toxic and slower-acting than photodieldrin against the German cockroach, indicating that this major metabolic product is not the actual toxicant in this species.