G. Groth, Schreeb Kh, V. Herdt
Jun 1, 1993
Citations
0
Influential Citations
32
Citations
Journal
Bulletin of Environmental Contamination and Toxicology
Abstract
N-methylamine~ N~N-dimethylamine, 2-aminoethanol, isopropylamine, aniline, N-methylaniline, N,N-dimethylaniline, quinone~ chloroacetaldehyde, cyclohexanol are widely used in various industrial fields (Merck Index 1989). They may therefore contaminate the environment. Their possible embryotoxic and/or teratologic potency has not been published before (GRS 1992)~ except that of aniline (Price et al. 1985, Hardin et al. 1987). This gap could be filled by the investigation presented here. Ferti l ized zebrafish (Brachydanio fetiD) eggs served as a well-recognized test object (Baumann and Sander 2984; Van Leeuwen et al. 1990) to elucidate morphological changes in the fish embryo during development and to discover reduction of the hatching rate induced by the above mentioned xenobiotics. From the results information important for the assessment of health risk are to be expected.