G. Skarping, C. Sangö, B.E.F. Smith
Apr 17, 1981
Citations
0
Influential Citations
39
Citations
Journal
Journal of Chromatography A
Abstract
Abstract A gas chromatographic method for the trace analysis of isocyanates in industrial atmospheres has been developed. It involves absorption of the isocyanates in dilute hydrochloric acid, where they are hydrolyzed to amines which after extraction with toluene react with heptafluorobutyric acid anhydride to form the correesponding amide. These are separated by gas chromatography on an OV-225 stationary phase and monitored by an elecron-capture detector. The method was applied to pheny isocynate, 2,4- and 2,6-toluene diisocyanate and to 4,4′-diphenylmethane diisocyanate. The detection limit is ca . 1 · 10 −4 mg isocyanate per m 3 air (151 sample), which means the sensitivity of the method is of the same order of magnitude as that of our previously developed liquid chromatographic method (C. Sango and E. Zimerson, J . Liquid Chromatogr., 3 (1980) 971).