Doseung Lee, K. Boo, Jin-kyu Woo
Apr 30, 2011
Citations
0
Influential Citations
0
Citations
Quality indicators
Journal
Journal of the Korean Society for Applied Biological Chemistry
Abstract
Bruceanol B, isolated from a soil microbe strain DS4, generated oxygen radicals in Bacillus subtilis lysates. Bruceanol B inhibited the trafficking of viral glycoprotein in virus-infected baby hamster kidney (BHK) cells. Bruceanol B also effectively inhibited syncytium formation in a dosedependent manner. However, glycoprotein synthesis was not affected by the compound. Results indicate that bruceanol B generating oxygen radical has inhibitory activity in the trafficking of viral glycoprotein of BHK cell.