V. Samoshin, V. A. Chertkov, Dmitriy E. Gremyachinskiy
Oct 11, 2004
Citations
0
Influential Citations
21
Citations
Journal
Tetrahedron Letters
Abstract
Abstract Protonation of trans-2-aminocyclohexanols leads to dramatic conformational changes: due to an intramolecular hydrogen bond a conformer with equatorial position of ammonio- and hydroxy-groups becomes predominant. The trans-2-aminocyclohexanol moiety has been used for pH-induced conformational switching of a crown ether and a podand.