Ying-zi Xu, K. Yakushijin, D. Horne
Nov 4, 1996
Citations
0
Influential Citations
12
Citations
Journal
Tetrahedron Letters
Abstract
Abstract The marine sponge alkaloid stevensine ( 3 ) has been synthesized from the related C 11 N 5 alkaloid, hymenin ( 1 ). The key transformation involves a regioselective protodebromination/transbromination event of 4′-bromohymenin ( 2 ) to install the olefin in 3 . Such processes are seldom used for synthetic purposes but appear to be highly applicable to the C 11 N 5 family of marine alkaloids.