Jason A. Miller, E. Hennessy, W. Marshall
Sep 11, 2003
Citations
0
Influential Citations
36
Citations
Journal
The Journal of organic chemistry
Abstract
trans-Cyclopropyl beta-amino acid derivatives can be synthesized in five steps with excellent enantioselectivities using a chiral (Salen)Ru(II) cyclopropanation catalyst in the key asymmetry-induction step. This facile synthesis proceeds with high overall yield and can be used to prepare a number of carbamate-protected (Cbz and Boc are demonstrated) beta-amino acid derivatives.