M. Choudhary, S. Musharraf, F. Shaheen
Jan 1, 2002
Citations
1
Influential Citations
27
Citations
Journal
Natural Product Letters
Abstract
Fermentation of (+)-androsta-1,4-diene-3,17-dione ( 1 ) with Cephalosporium aphidicola for 8 days yielded oxidative and reductive metabolites, androst-4-ene-3,17-dione ( 2 ), 17 g -hydroxyandrosta-1,4-diene-3-one ( 3 ), 11 f -hydroxyandrosta-1,4-diene-3,17-dione ( 4 ), 11 f -hydroxyandrost-4-ene-3,17-dione ( 5 ), 11 f ,17 g -dihydroxyandrost-4-ene-3-one ( 6 ) and 11 f ,17 g -dihydroxyandrosta-1,4-diene-3-one ( 7 ). The fermentation of 1 with Fusarium lini also yielded metabolites 3-7 . The structures of these metabolites were elucidated on the basis of spectroscopic techniques.