D. N. Nicolaides, K. Litinas, Ioannis Vrasidas
Jul 1, 2004
Citations
0
Influential Citations
12
Citations
Journal
Journal of Heterocyclic Chemistry
Abstract
The unexpected formation of 3-aryl-5-arylamino-1,2,4-oxadiazoles took place, when arylamidoximes reacted thermally with ethoxycarbonylmethylene(triphenyl)phosphorane. Furoxans, nitriles, ureas were also isolated suggesting aryl cyanide oxides as intermediates. 3-Aryl-5-arylamino-1,2,4-oxadiazoles were formed via an aryl migration from the carbon atom to the nitrogen atom of the amidoxime, and the structure was further proved from the X-ray crystal structure of the N-(4-bromobenzoyl) derivative.