Jianwen Hou, Yudong Fei, Wei Li
Oct 14, 2018
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Influential Citations
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Journal
British Journal of Pharmacology
Abstract
9‐Phenanthrol, known as a specific inhibitor of the transient receptor potential melastatin 4 (TRMP4) channel, has been shown to modulate cardiac electrical activity and exert antiarrhythmic effects. However, its pharmacological effects remain to be fully explored. Here, we tested the hypothesis that cardiac sodium current inhibition contributes to the cardioprotective effect of 9‐phenanthrol.