A. Verma, Saket Patel, M. Meenakshi
Jan 25, 2015
Citations
1
Influential Citations
61
Citations
Journal
Chemical communications
Abstract
A synthetic method has been developed for the preparation of biologically important isoindolinones including indoprofen and DWP205190 drugs from 2-alkylbenzamide substrates by transition metal-free intramolecular selective oxidative coupling of C(sp(3))-H and N-H bonds utilizing iodine, potassium carbonate and di-tert-butyl peroxide in acetonitrile at 110-140 °C.