B. Steinbaugh, H. W. Hamilton, J. Prasad
May 21, 1996
Citations
0
Influential Citations
11
Citations
Journal
Bioorganic & Medicinal Chemistry Letters
Abstract
Abstract In a study of 4-hydroxy-pyran-2-ones as possible inhibitors of HIV protease, a series of compounds were synthesized following the Topliss operational scheme for substitution on a phenyl group at the 6 position of the pyrone. In addition, a number of compounds with polar substituents were made.