S. Chapyshev
Nov 1, 2011
Citations
0
Influential Citations
11
Citations
Journal
Journal of Fluorine Chemistry
Abstract
Abstract 3-Chlorotetrafluoropyridine and pentafluoropyridine readily react with an excess of sodium azide in dimethylsulfoxide at room temperature to give corresponding 2,4,6-triazido-3-chloro-5-fluoropyridine and 2,4,6-triazido-3,5-difluoropyridine in high yields. The reaction of asymmetric 3-chlorotetrafluoropyridine with two equimolar amounts of sodium azide under similar reaction conditions occurs regioselectively to give 2,4-diazido-5-chloro-3,6-difluoropyridine as a sole product. 19 F, 13 C and 15 N NMR spectral characteristics of the triazides suggest that these compounds can be of interest as cross-linking reagents for polymer chemistry and as starting materials for organic synthesis.