Ya Li, Ying Ma, Zhi-feng Lu
Aug 29, 2012
Citations
0
Influential Citations
10
Citations
Journal
Tetrahedron Letters
Abstract
Abstract The unprecedented nucleophilic tribromomethylation of N-(tert-butanesulfinyl)imines with bromoform has been shown to be a highly stereoselective and practical method for the synthesis of enantiomerically pure α-tribromomethyl amines. THF has proven to be the best solvent in this addition reaction. By changing the reaction solvent from THF to DMF, 2,2-dibromoaziridines can also be synthesized directly from bromoform and N-(tert-butanesulfinyl)imines under similar reaction conditions.