Jun Jiang, Miao Zhang, Wenbin Wu
Oct 11, 2017
Citations
0
Influential Citations
4
Citations
Journal
Synlett
Abstract
Abstract The convergent synthesis of two biologically significant classes of trisubstituted hexahydroimidazo[1,2-a]pyridine and 1,4-diazepane derivatives from readily available aromatic aldehydes, ketones, and ethane-1,2-diamine is reported. This protocol is promoted by the highly effective l-phenylalanine triflate catalyst through intermolecular annulation, and tolerates a variety of functional groups with excellent yields.