Olivier Marrec, T. Billard, J. Vors
Nov 2, 2010
Citations
0
Influential Citations
56
Citations
Journal
Advanced Synthesis & Catalysis
Abstract
The reaction of tetrabutylammonium triphenyldifluorosilicate with 2,4-dinitro(trifluoromethoxy)benzene, in acetonitrile and under microwave irradiation, generates a trifluoromethoxide anion which is able to substitute activated bromides (benzyl bromide, cinnamyl bromide), as well as, to some extent, alkyl iodides. Aliphatic trifluoromethyl ethers are thus formed. This is the first example of the nucleophilic displacement of the trifluoro-methoxy group from an activated aromatic ring.