V. Sosnovskikh, B. Usachev, D. Sevenard
May 1, 2005
Citations
0
Influential Citations
22
Citations
Journal
Journal of Fluorine Chemistry
Abstract
Abstract Reactions of N -substituted 2-polyfluoroalkyl-4-quinolones and 8-aza-5,7-dimethyl-2-polyfluoroalkylchromones with (trifluoromethyl)trimethylsilane proceed mainly as a 1,4-nucleophilic trifluoromethylation to give N -substituted 2,2-bis(polyfluoroalkyl)-2,3-dihydroquinolin-4(1 H )-ones and 5,7-dimethyl-2,2-bis(polyfluoroalkyl)-2,3-dihydro-4 H -pyrano[2,3- b ]pyridin-4-ones after acid hydrolysis. Similar reaction with 2-trifluoromethyl-4 H -thiochromen-4-one proceeds as a 1,2-addition to give 2,4-bis(trifluoromethyl)-4 H -thiochromen-4-yl trimethylsilyl ether.