P. Munier, D. Picq, D. Anker
Dec 17, 1993
Citations
0
Influential Citations
22
Citations
Journal
Tetrahedron Letters
Abstract
Abstract The four 5-deoxy-5,5,5-trifluoro-D and L-ribo and -lyxo furanoses were synthesized from lactones using CF 3 SiMe 3 in 5 or 6 steps and 30–40 % overall yield. The key step was a stereoselective reduction of 1,1,1-trifluoro-2-ketoses with LiAlH 4 or NaBH 4 at an anomeric centre.