Atul T. Manvar, D. O’Shea
Nov 1, 2015
Citations
0
Influential Citations
8
Citations
Journal
European Journal of Organic Chemistry
Abstract
The synthesis of the reagent 2,2-bis(trimethylsilyl)-1,3-dithiane was directly achieved in an excellent yield from 1,3-dithiane in one step. The bench-stable reagent can be utilized for Peterson olefinations using either TMSOK/Bu4NCl or fluoride ion as promoter of α-silyl carbanion formation, thereby generating ketene dithioacetals, which are versatile intermediates in organic synthesis. Olefination reactions were successfully achieved with aromatic, heteroaromatic, aliphatic aldehydes and ketones.