W. A. Wilson, M. T. Clark, T. Pellmar
Apr 22, 1977
Citations
0
Influential Citations
42
Citations
Journal
Science
Abstract
The commonly used buffering agent tris(hydroxymethyl)methylamine (tris) antagonizes the action of iontophoretically applied acetylcholine on neurons of Aplysia californica. Concentrations of 5 to 10 millimolar tris markedly reduced both excitatory and inhibitory responses.