A. Lasisi, B. Ayinde, A. Adeleye
Mar 1, 2015
Citations
1
Influential Citations
19
Citations
Journal
Journal of Saudi Chemical Society
Abstract
Abstract In addition to lupeyl steryl ether ( 1 ) and 3-oxo-11α-hydroxyl-20 (29) lupen ( 2 ), a new lupeol-3-isovanniloyl ester ( 3 ) was isolated from Paullinia pinnata . Using detailed 1D and 2D NMR spectra and comparison with the published data, the new compound was characterised as 3- O -isovanilloyl-3 R ,5 R ,8 R ,9 R ,10 R ,13 R ,14 S ,17 S ,18 R ,19 R -lup-20(29)-en, for which the trivial name Paullinoyl was proposed. Compound 3 demonstrated significant antibacterial activity on the tested strains (MIC 15.2–30.20 μg/ml). The antibacterial activities obtained in this study confirmed the use of P. pinnata in traditional medicine for treating bacterial infections.