Claire Empel, T. V. Nguyen, Rene M. Koenigs
Jan 5, 2021
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0
Influential Citations
22
Citations
Journal
Organic letters
Abstract
Herein, we describe the application of a nonbenzenoid aromatic carbocation, namely tropylium, as an organic Lewis acid catalyst in O-H functionalization reactions of diazoalkanes with benzoic acids. The newly developed protocol is applicable to a wide range of diazoalkane and carboxylic acid substrates with excellent efficiency (43 examples, up to 99% yield).