Ying-xia Tan, Chong Chen, Ying-li Wang
Apr 1, 2012
Citations
0
Influential Citations
25
Citations
Journal
The Journal of Gene Medicine
Abstract
Melittin is a commonly used cell‐penetrating peptide (CPP) for improving branched polyethylenimine (BPEI)‐mediated gene transfection. However, its application is limited owing to the cytotoxicity generated by the lytic activity at neutral pH. In the present study, we report two truncated peptides from melittin and florae with improved transfection efficiency.