Susanna Sampaolesi, S. Gabrielli, R. Ballini
Oct 4, 2017
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Influential Citations
10
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Journal
Advanced Synthesis & Catalysis
Abstract
A new simple and efficient synthesis of 6-nitroindoles, starting from N-carboxylalkyl pyrrole-2-carboxaldehydes and protected β-nitro ketones, has been developed. The method involves two distinct domino processes, respectively performed under flow chemical conditions and microwaves irradiations. 6-Nitroindoles were produce from good to excellent overall yields.