Min Zhang, Y. Gong, Weizhou Wang
Nov 1, 2013
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0
Influential Citations
32
Citations
Journal
European Journal of Organic Chemistry
Abstract
A two-step sequence to ethyl α-fluorocyclopropanecarboxylates has been developed. Ethyl α-chlorocyclopropanecarboxylates were first obtained through a Michael-initiated ring closure reaction of terminal electron-deficient olefins with ethyl 2,2-dichloroacetate under mild basic conditions. Subsequent smooth conversion into the corresponding monofluorinated analogues in good yields was through a halogen ex