Barbara Bernardim, A. Burtoloso
May 20, 2014
Citations
0
Influential Citations
5
Citations
Journal
Tetrahedron
Abstract
Abstract An expedited synthesis of the bioprotective agent JP4-039 is described from N-Boc- l -leucinal in 50% overall yield. The synthesis involves the use of an α,β-unsaturated diazoketone as the key intermediate, followed by a photochemical Wolff rearrangement in the presence of 4-amino-TEMPO (4-AT).