N. Willand, B. Folléas, C. Boutillon
Jul 16, 2007
Citations
0
Influential Citations
16
Citations
Journal
Tetrahedron Letters
Abstract
Abstract We describe a novel strategy for the synthesis of N-substituted nortropinone derivatives starting from tropinone. The key step of our synthesis is a reactivity umpolung of tropinone, which yields 8,8-dimethyl-3-oxo-8-azonia-bicyclo[3.2.1]octane iodide (IDABO) as a stable and convenient synthetic equivalent of cycloheptadienone.