Valérie Lefebvre, T. Cailly, F. Fabis
Mar 17, 2010
Citations
0
Influential Citations
35
Citations
Journal
The Journal of organic chemistry
Abstract
A general two-step synthesis of substituted 3-aminoindazoles from 2-bromobenzonitriles involving a palladium-catalyzed arylation of benzophenone hydrazone followed by an acidic deprotection/cyclization sequence is described. This procedure offers a general and efficient alternative to the typical S(N)Ar reaction of hydrazine with o-fluorobenzonitriles.