H. Bonacorso, E. Pittaluga, Liliane M. F. Porte
Aug 10, 2015
Citations
0
Influential Citations
4
Citations
Journal
Synlett
Abstract
Abstract Metal-free electrophilic fluorination, promoted by Selectfluor, of pyrazoles with methylene groups (CH2X), in which X = OH, OMe, F, N3, and NHMe at the C-4 position furnished the 4-fluoro-pyrazole products from unexpected C–C bond cleavage, at moderate to good yields. Otherwise, under the same reaction conditions, when X = NEt2 or SPr, the oxidation product 4-formyl-pyrazole was obtained.