Hong-Jun Pi, Jin Dong, Na An
Sep 12, 2009
Citations
0
Influential Citations
49
Citations
Journal
Tetrahedron
Abstract
Abstract TsCl (p-toluenesulfonyl chloride), a commercially available organosulfonyl chloride, has been widely used as a stoichiometric dehydrogenation reagent in the transformation of ketoximes into corresponding amides via the Beckmann rearrangement. It has been now found to catalyze the Beckmann rearrangement with high catalytic efficiency, converting a wide range of ketoximes into their corresponding amides under mild condition with good to excellent yields (up to 99% of yield with 1–5 mol % of catalyst loading).