S. Abbas, K. El-Bayouki, W. Basyouni
Apr 18, 2016
Citations
0
Influential Citations
46
Citations
Journal
Synthetic Communications
Abstract
ABSTRACT Isatoic anhydride has attracted a great deal of attention in recent decades. A review of the methods of preparation of all known quinazoline and quinazolinone derivatives is given herein. Isatoic anhydrides react with some nitrogen nucleophiles, followed by cyclocondensation by electrophiles, to produce several quinazoline and quinazolinone derivatives. These compounds find use as medicinal and pharmacological substances. GRAPHICAL ABSTRACT