A. Pandey, D. Dwivedi
Nov 21, 2017
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Influential Citations
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Citations
Journal
International research journal of pharmacy
Abstract
A simple, convenient and accurate visual titrimetric method for the determination of Pheniramine maleate (PM) in pure form and in their pharmaceutical formulations Avil (tablet and injection) using Pyridinium fluoro chromate (PFC) as an oxidant is described. The titrimetric method is based on the oxidation of the drugs in sulphuric acid medium by known excess of Pyridinium fluoro chromate and iodometric determination of the unreacted Pyridinium fluoro chromate(PFC). To examine the accuracy and precision of results percentage error, standard deviation(SD) and coefficient of variation (CV) were also calculated for each sample. Proposed method was validated by recovery analysis by drug addition method of drug.